After her father's death Sabrina Brooks, the heiress to the Brooks Chemical Company, is trying to pick up the pieces and put everything together. She soon understands that her new position and assets allow her to benefit the oppressed.

Intrigued by the notion of conducting a guerrilla campaign against drug gangs in New York City, she accesses top-secret archives detailing government contracts for chemical weapons research. With her exceptional skills in chemistry, she concocts weaponry for her own use and becomes a vigilante called the Nightcrawler.

After NYPD undercover officer Hoyt Wexford becomes friends with her and learns of her secret identity, the two wage war against the ruthless drug cartel called the Octagon and their mysterious leader, Reaper. But even with their resourcefulness and teamwork, can they bring the fiendish arch-criminals to justice?